NEXT-ERA DNA DAMAGE RESPONSE THERAPIES

About Onco-Innovations

About Onco-Innovations

Onco-Innovations is a Canadian-based company dedicated to cancer research and treatment currently leading the development of Polynucleotide Kinase Phosphatase (PNKP) inhibitors, a unique and emerging class of DNA Damage Response (DDR) therapies.

By combining novel, proprietary drug candidates with advanced nanoparticle (NP) tumor delivery and an AI-native discovery platform, we aim to redefine the treatment of cancers resistant to traditional therapies with its lead drug candidate, ONC010: a nanoparticle-encapsulated PNKP inhibitor.

ONC010ᵀᴹ

The Next-Generation Drug Formulation

Our Proprietary Lead Drug Candidate ONC010 Utilizes 100% Licensed PNKP Inhibitor Technology

Our Proprietary Lead Drug Candidate ONC010 Utilizes 100% Licensed PNKP Inhibitor Technology

Proprietary Formula

Aims to prevent DNA repair to eliminate cancer cells

Enhanced Delivery

Nanoparticles ensure precision targeting

Optimized Results

Designed to work with chemo/radiation/surgery to potentially improve outcomes and reduce side effects

DNA Damage Response Inhibitors (DDRI) is becoming
one of the fastest growing areas in oncology

DNA Damage Response Inhibitors (DDRI) is becoming
one of the fastest growing areas in oncology

*See Appendix 8 for forecast details

Onco-Innovations pioneers cancer research, developing cutting-edge therapies to prevent and treat cancer. With exclusive global rights to groundbreaking technology targeting solid tumors, we set new benchmarks in oncology, improving patient outcomes and offering hope.

Get in Touch with Us

Onco-Innovations Limited

Tel: 1 (888) 261 – 8055

investors@oncoinnovations.com

1309 – 7th Street SW
Calgary, Alberta, Canada
T2R 1A5

Tel: 1 (888) 261 – 8055

investors@oncoinnovations.com

1309 – 7th Street SW
Calgary, Alberta, Canada
T2R 1A5

Onco-Innovations pioneers cancer research, developing

cutting-edge therapies to treat cancer.

Reach Us

1309 – 7th Street SW
Calgary, Alberta, Canada
T2R 1A5

investors@oncoinnovations.com

+1 (888) 261–8055

© 2025 Onco-Innovations Limited | All Rights Reserved

Onco-Innovations pioneers cancer research, developing

cutting-edge therapies to treat cancer.

Reach Us

1309 – 7th Street SW
Calgary, Alberta, Canada
T2R 1A5

investors@oncoinnovations.com

+1 (888) 261–8055

© 2025 Onco-Innovations Limited | All Rights Reserved

Onco-Innovations pioneers cancer research, developing

cutting-edge therapies to treat cancer.

Reach Us

1309 – 7th Street SW
Calgary, Alberta, Canada
T2R 1A5

investors@oncoinnovations.com

+1 (888) 261–8055

© 2025 Onco-Innovations Limited | All Rights Reserved

Onco-Innovations pioneers cancer research, developing

cutting-edge therapies to treat cancer.

Reach Us

1309 – 7th Street SW
Calgary, Alberta, Canada
T2R 1A5

investors@oncoinnovations.com

+1 (888) 261–8055

© 2025 Onco-Innovations Limited | All Rights Reserved